Nuclear lipids play roles in regulatory processes, such as signaling, transcriptional regulation, and DNA repair.In this report, we demonstrate that nuclear lipids may contribute to Ki-67-regulated chromosome integrity during mitosis.In COS-7 cells, nuclear lipids are enriched at the perichromosomal layer and excluded from intrachromosomal regions
Obesity or BMI Paradox? Beneath the Tip of the Iceberg
The obesity paradox refers to extant evidence showing that obesity in older subjects or in patients with several chronic diseases may be protective and associated with decreased mortality.A number of mechanisms have Singlet been postulated to support the existence of obesity paradox; however, marked heterogeneity was found across studies and this h
The Path of Building Maritime Community with Shared Future Based on the Development of Deep-Sea Marine Energy
In order to practice the concept of "maritime community with shared future" and accelerate the construction of a maritime power, this paper reviewed the strategic significance and value of deep-sea REC ACCEL marine energy development, and summarized the research status and application prospects of ocean thermal energy conversion (OTEC), and put for
Interconnections of Pseudomonas aeruginosa Quorum-Sensing Systems in Intestinal Permeability and Inflammation
ABSTRACT Quorum sensing (QS) is a highly conserved microbial communication mechanism based on the production and sensing of secreted signaling molecules.The recalcitrant pathogen Pseudomonas aeruginosa is a problematic nosocomial pathogen with complex interconnected QS systems controlling multiple virulence functions.The relevance of QS in P.aerugi